Yes, for deleting preferences. Are you trying to repair permissions?
As I said, it's a permissions problem. Her's John's directions for you:
I beleive this is a bug in the Installer where it leaves ~/Library/Preferences/Adobe InDesign/Version 7.0 marked read-only, and then InDesign crashes early in the startup process (in the "AdobeBIB" component) when it tries to write its preferences and it fails to do so.
This is a longstanding bug and nobody understands why the installer messes it up.
So the answer is to either trash the above folder, or to hit Cmd-I (File Info) on it in the Finder and make sure it is set to read-write under Sharing and Permissions.