It's not likely, especially if the files work for awhile, then fail.
What I'm seeing is blank pages inserted into the document that is, pages aren't added to the document but the pages that were there appear blank, except for my Master page elements. The text is still linked but not visible, almost as if it were covered up. In some pages of the document, the paste board will be extended all the way to the margins of my monitor, visible when the pages are viewed at 50%. I'd love to be able to show a pdf of it. PRC
try exporting the file to .idml. See Remove minor corruption by exporting
While that might "fix the file," if doesn't address the root cause, which is probably some other software you have running, perhaps a third-party plugin, such as a font manager auto-activation plugin.