I am an IT Professional working for a major University in Missouri. We have an Apple computer lab of 26 20" iMacs, all running Adobe Creative Cloud with an Enterprise license. This license includes Adobe Muse (with its own serial number). We use Active Directory to manage users/group policies on all computers, and manage users on our Apple computers.
According to Adobe's support site, you can create a prov.xml file using APTEE and then apply it to serialize the Muse product installation for a computer lab environment.
I can only get this to work for EXISTING users. When a NEW user logs in to his or her account, they run Muse, and it asks for a subscription, as though Muse is not serialized. According to Adobe, you click on Existing Subscription anyway, enter your Adobe ID, and then it should still open. It doesn't..........it says the "subscription does not have a license for Adobe Muse" and gives the option to BUY or QUIT.
I am not Adobe (just another user) but a link that may help
Chat Now button near the bottom for Activation and Deactivation
If I remember correctly, I would advise you to update your Creative Cloud Packager and recreate the deployment package. More, at http://helpx.adobe.com/creative-cloud/packager.html
If you are still having issues, check in the proper forum: http://forums.adobe.com/community/download_install_setup/creative_suite_enterprise_deploym ent
Or contact Adobe support.