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You can to an extent. It's not as good as AE where it will interpolate frames. Here's what you can do...
Put your artwork inside of a symbol. This is the equivalent of a composition in AE.
Place your symbol in the stage.
Click it once and its properties will appear in the Properties pane.
Look under the "Looping" section of the Properties window.
You can change the options to "Loop", "Play Once", or "Single Frame".
The "First" number corresponds to the frame number inside your symbol.
You can change these settings for every key frame you set.
The biggest difference between Flash and AE is that tweening a time-remapped symbol won't interpolate frames. Instead it will mess up your time-remapping. The best practice is to put your time-remapped symbol inside another symbol, and tween and puppet the new symbol instead.
You can create a mouth shapes for lip sync and put them in a symbol. Then set the symbol to "Single Frame" and set keyframes in your timeline to call up each mouth shape to match your audio. Then to move your mouth symbol around on your character's face, you can put the mouth symbol into a new symbol, and just puppet the new symbol.
Thanks alot Kristofer!
It very helpful I will try it
No problem! Glad I could help.