Do you place it in an existing frame? Might be that the frame is flipped or scaled?
That's what I thought was happening with my coworker as well, but she is simply just dragging and placing the image into an empty area. The file she is working with is one that was converted from quark with an add on, would that have any relation to why this is happening?
Converted documents from Quark you have to clean up in the beginning by exporting to IDML or INX, opening the IDML or INX and saving as new INDD. The conversion from Quark is not flawless.