Are you using any of the supported Safari audio file types in this project (MP3, AAC, WAV)?
Yes, I use 3 Audio formats for cross broswers. mp3,ogg, and aac. I also use "buzz.jp".
Do you think it might be some bug in "buzz.jp"?
Possibly an encoding issue, more than anything, with that particular audio file.
Care to share the project url for others to test in Chrome?
Are you using Edge Animate v3? It supports audio now.