I am using a brand new computer running Windows 7 64-bit.
I am also using Adobe CC for the first time. Downloaded InDesign, Photoshop, Illustrator, and Acrobat last week, and I'm using mostly InDesign so far.
My issue: When I switch from InDesign to, say, check my Outlook in box, sometimes I can't click on anything at all, including "Show Desktop." I am only able to get functionality back by doing a Ctrl-Alt-Del and then cancelling the Task Manager when it appears. Then the mouse forgets that I mouse left-handed, for a few seconds. After that, everything works right.