Can you try running the program as an administrator and let us know if you still get this error?
Thank you for your reply, I would have replied sooner but I couldn't sign in to Adobe. My issue was solved by trying another method:
I got my first runtime error when I opened a text document with Dreamweaver that I created from my desktop, at first the file extension was .css.txt, I made it a .css file and if I right clicked and "opened with" Dreamweaver I would get the runtime error.
Since then I have created a site definition and created everything within Dreamweaver and had no issue with runtime errors.
I was following a tutorial on Slicing and really wanted to carry it through but instead I resized each image and put into Dreamweaver's prebuilt template. I had to settle due to time sensitivity.
I will certainly try slicing on my own time from here on, lol
Thank you for posting your solution. Much appreciated. It will help other users with a similar issue.