Are you using Mac OSX v10.9? I've noticed that Mac OSX v10.9 incorrectly sets the permissions for the preferences folders, which prevents some files from being written, causing problems like this.
Got to the preferences folder and make sure that this entire folder and all of its contents are set to read/write, not just read-only:
Yes, I am running 10.9. However, my preferences folder (and sub folders) already have read and write enabled. So, your suggestion doesn't fix anything. Any other ideas? If I can't figure this out on my own, I guess I'll try my hand at adobe phone support...