Seems to be a common problem - did you resolve it as I have the same issue with PS 2015 in Windows 10
Could you please let me know the exact version of Photoshop and Lightroom installed on your computer ?
Also which file format are you trying to Edit from Lightroom to Photoshop ?
My problem was resolved by the techs at Adobe. It seems that the automatic reinstall performed by the Win 10 upgrade sets everything to "run as administrator". The simple solution they told me was to disable this limitation and now everything works as it should.