I am having an issue in PS CS6 (on a Mac) where in the middle of working on a file, it gets corrupted by filling in a grid of squares in my layer masks as well as deleting out those same sections of misc layers throughout the file. I have reset the preferences, cleaned up the file. Renamed it to another file and 2 weeks later it is doing the same thing. Luckily I had my main subjects as smart objects and it saved them. This second time I just closed it out and opened it again and it is fine. Anybody else have an issue with this? Also it runs really slow these days on my MacBook Pro Retina 2.6 Core i7 with 16gb Ram.