I would think you should ask this in a Microsoft, Apple or Linux virtual desktop forum. I would think its how well the mouse operations are vitalized by the VDI application. Most likely the lag is due to the VDI operation.
We are using Vmware Horizon View. I have openup a post in the Vmware forum about this issue a few weeks ago. No response so far. A lot of other programs do not seem to be affected by this issue. Only graphical applications like Photoshop, CAD or Gimp are effected.
A few weeks ago we went to Vmworld in Barcelona. We visited some good sessions from Nvidia on grapics in virtual machines. We also visited a presentation about a big archtict firm that managed to fully virtualize all of their workstations and now work from all over the globe on any end-point that the users would like. How did they manage to pull that off without mousse lag? Do other Photoshop users also have this problem?
It may well be the way these application are written to use different OS api then other applications and how the virtual devices are programmed by Vmware to reflect hardware interrupts and mouse events to virtual machines some API may perform better then others. I don't not think Application developers will change their products design to work better on different virtual machine applications. They want the their application to work without problem in the native environment