I have gotten lots of good help through the community. As a result I have de-installed CS4. Run the adobe cleaner. And re-installed CS4. Many annoying bugs were fixed but I still can't print from photoshop to my epson 3880..... I used to be able to do this and I still can print from other programs. I've done troubleshooting with Epson and it's clearly a Photoshop issue. Are there any other suggestions before I throw in the towel on this otherwise perfectly good program and pay monthly for the cloud?
I'm really appreciative of the time you take to answer!
If your epson 3880 prints from apps outside CS4, then this is most likely a Preferences problem and requires a reset.
Hold down cmd-opt-shift and start Photoshop CS4. You will see a Reset dialog. Agree to the reset.