You have not provided any system information or other details, so we don't even know where to begin. Due to the specifics of E3D using hardware features it might not be a good idea to render directly through AME, though. Simply render a normal Quicktime movie or an image sequence and convert it in a second step.
Sorry about that. Yes, it's probably a hardware problem. Here's my system:
win 8, 64 bit
intel core 2 duo processor
graphics card nvidia GeForce GT 240
Since I configured the PC for gaming, it's probably safe to assume that it's not quite up to par for animations...
Good to know that the Quicktime>AME is a viable workaround. I'd been doing that but just wondered if there was any way I could skip a step.
Wait...what version of AE are you running? It's been years since a version can run on only 2GB of RAM! I usually recommend 16GB at the low end these days.
Guess I know what to ask for for Christmas! LOL.
Running AE CC. It's slow, and obviously can't handle everything. Slow and steady, as they say...