Please help us other users here help you ... we can't 'see' through the blasted internet cables, you know?
Some basic computer specs ... OS, CPU, sound card, video card, this sort of thing is necessary. Plus ... a screen grab of what options the preferences panel does show you would be useful.
Late 2013 MacPro 3.7GHz Quad-Core Intel Xenon E5
AMD FirePro D700 6114mb
M-Audio Fast Track Pro USB Audio Interface
Attached is a screen shot of my preferences and how M-Audio Fasttrack is no longer a possibility. (again audio isn't playing back through the desktop speakers either) (all other applications have audio playing back through both interface and desktop however)
At this point, I'd trash the preferences file for PrPro first ... easy to do, there's stuff to tell you where that is in the Mac side ... I'm a PC person & don't remember that folder tree. Probably won't do it, but worth a few seconds. Every once in a while that does fix something like this and it's a quick one to get outta the way.
Did you reboot since updating PPro?
This did it! Thank you! My Interface is still not listed as on the options BUT audio is coming out of the monitor speakers!! Thanks again