Can you share a sample PDF to test it? A quick test with Trebuchet MS doesn't show the problem.
This is the .PDf in question: http://www.waldronhr.com/images/stories/Position_Specifications/seattleaquarium_devdir.pdf
It looks fine when viewed in Safari, but when viewed on Chrome, some of the white text looks bold (it shouldn’t) and other lines do not appear bold.
Thanks for any suggestions!
Jessica Crump, Director of Marketing and Communications
[Personal info removed by moderator]
I don't see a problem if I open it on Chrome on a PC using Window 8.1. I see the problem if a open it on Chrome on a Mac using Yosemite 10.10.1. My only take is that Trebuchet MS produces an Embedded Subset/True Type (CID) that somehow affects the appearance on Chrome on a Mac. This is a guess though. In the past selecting the text and disabling ligatures helped. You might want to give it a try.
The font looks fine in Acrobat and Reader as well.
The problem is that there are many substandard PDF readers (apparently Chrome is one of them, Preview from the Mac is another). All you can do is aim for it to look the best in Reader and Acrobat, I'm afraid. They are the PDF readers which are fully following the PDF specification.