I was working on Photoshop CS 5 on windows 7 and i got a blue screen. After restarting the PC I launched photoshop and I got an error "you can't open the work file because the file is blocked or you don't have permission to open it (...) and then after clicking OK another error: "you can't initialize photoshop, because the work file is blocked ...". Even if I manage to open photoshop, I cannot work because i get the meessage about the full scratch disks. I've got plenty of room on my scratch disks. I even tried to reinstall Photoshop, it didnt help. Please help me, I cannot work.
Repair your disks with checkdisk and also fix your botched permissions.