I'm Having the same problem.
Same problem - and the library IT people are very puzzled... Happened to me after that freebie Win 10 upgrade from MS. It's been a problem in several areas. I shouldn't have upgraded to 4.5 but also I'm not certain that was what did it. Have tried deleting and reinstalling the ADE app but no luck. I also get this error: E_LIC_ALREADY_FULFILLED_BY_ANOTHER_USER
And this one:
Adobe Chat was not available for ADE help - just short of rude when they blew me off. Seems to me that our library IT people are the key to the solution - pressure on Adobe to collate solutions, etc. My library contact IS actively looking into it but it's a slow process what with the workload she has at the Help Desk. But I am confident she will get somewhere on this problem.
It seems like everyone's been waiting a long time for help with this.
I've just started getting the same error message, like you, after upgrading to Windows 10.
I've uninstalled and reinstalled; also deactivated/deauthorized and reactivated/reauthorized; also used ADEPT delete instructions from other discussions about apparently similar errors.
Did anyone ever get an answer? Two to ten MONTHS is a long time to wait for help from Adobe!
Hi mikec27379597 - I imagine you got an answer long ago, but just in case: running ADE as Administrator seems to fix this problem.