When it happened to me, it turned out that my permissions to the Application Support folder was unintentionally changed during an update, causing the problem.
A Terminal command fixed it. Copy and paste into Terminal. You need to be allowed to administer this computer from your account.
If you are asked to enter a password, enter it blindly, because usually there are no dots and cursor movement when you do.
sudo chmod -R 777 /Library/Application\ Support/Adobe