try resetting your preferences -
adobe media encoder: https://forums.adobe.com/thread/1713540
after effects: http://helpx.adobe.com/after-effects/using/preferences.html
muse (mac): https://forums.adobe.com/thread/1246022?tstart=0
if that fails, uninstall, clean (http://www.adobe.com/support/contact/cscleanertool.html) and reinstall
I followed this link:
but I didn't understand how to do any of it. How do you recreate the preference files? The only thing I understood how to do was the steps with the registry entry, which I did, and it still wouldn't save. I'm not sure what how to do the things suggested as I'm not very computer savvy.
Also, I should mention I'm doing this on my second computer. I had this problem on my normal computer (with saving) so I deactivated it, installed it on my older computer I hardly ever use, and the problem still persists.