Why do you want todo it? What is causing a problem to you?
InDesign lets you assign both a CMYK and RGB profile to the document. The CMYK profile handles the display of and conversion to CMYK colors, the RGB profile handles display of and conversion to RGB colors. You can change the document profile assignments via Edit>Assign Profiles..., or you can convert document colors and swatches via Edit>Convert to Profile... If you use convert the color values are changed and the new profile is assigned.
From Edit>Assign Profiles... you can choose Discard (use current working space). In that case the document has no profile and the color will be displayed by whatever profile happens to be set as the working space.
That's written. But Srinee must be aware that a color without a profile does not make any color as a color space needs for its definition the numeric values, the color mode and color profile.
Every color is shown with a color profile, if you delete the color profile from the file it will show the color with any profile but not necessary with the correct profile. Without a profile, color valors are useless numbers.