I have Windows 10 installed on two of my computers (with Premiere Elements and Photoshop Elements versions, including 12/12.1), and my impression of the Premiere Elements side of things (my special interest) is that the Premiere Elements successes and failures are the same before and after upgrade to Windows 10 64 bit.
Do you have a specific question about your Premiere Elements 12/12.1 on Windows 10 workflow? Photoshop Elements questions should be explored in the Adobe Photoshop Elements Forum to take advantage of the expertise there. But, I can put on a Photoshop Elements hat for some Photoshop Elements questions.
Thanks for your help.