I have followed Adobe Help guidance and made a registry entry in the Shell Users folder has advised. Still get 'Assertion failed' when trying to load Lightroom
If you had made the changes in the registry as per : https://helpx.adobe.com/lightroom/kb/lightroom-error-assertion-failed-update.html
Then I would request you to please uninstall and reinstall Lightroom on your computer.
Thank you Tanuj. All is now fine