Pretty direct question. I'm branding an event in Vegas that has a wall with 16 (48x41") panels. The space between them is 1". I want to create an art piece that spans over multiple panels. How would you do this if you couldn't do it in one big piece? I'm guessing the spacing will be a bit tricky.
I'd be far more inclined to do that in Illustrator.
Depends on how you intend to handle the gap, but I'd be inclined, if working in ID, to set up each tile as a page.