I am sorry for the inconvenience caused to you.
This issue has been reported to us already and our engineering team is working on it.
Please refer the below link.
Hi Mrinmay Majhi!
Thanks for your quick response, but I rolled back to 2015.1.1 and also to the very first Lightroom 6 release and it didn't work.
I tryed to install LR 5, but as I'm a Creative Cloud user, I don't have a serial number, so I could not activate and use it to check if tethering was working in version 5.
Do you have any other clue on that? I need this badly for a job this week!!
Thanks a lot!
Please follow the below steps to troubleshoot tethered capture in Lightroom.
However, being a Creative Cloud subscriber, you are entitled to use Lightroom 5.
Please follow the steps for Lightroom 2015.1.1 and also share the error message to help you with the activation of Lightroom 5.
Hi Mrinmay Majhi,
There is no problem with Tethered Capture itself, the problem is that upon importing the image, the development preset I choose to be automatically applied is not being applied. I have to manually apply the preset after importing which is annoying and time consuming.
Anyway, I tried the steps in the troubleshooting guide, and everything worked normally as expected. Just the above is still not working.
About Lightroom 5, after installation there is no error message. It asks me to TRY or insert a SERIAL NUMBER. I don't want to try the software, as I am entitled to use LR5... But I don't have a serial number, so I can't continue and I cant even try to use LR 5 as well.
Exactly the same problem here with a Nikon D810. Previous and presets don't apply on capture. Even clicking them in the preset menu does nothing unless another preset is clicked first.
Hello Mrinmay Majhi
I have the exact same issue with LightroomCC Version 2015.4. If I tether via another program and then import the files automatically, the preset gets applied to every single image. But when I tether directly via LR, the preset does not get applied reliably. All images get the preset in the library quick develop module, but the preset ist not being applied to the image.
I have exactly the same problem, also on Lightroom CC 2015.4 on a Windows 10 PC.
Same problem here. Macintosh. 10.11.4 - LR2015.5
I also have the same problem with the latest automatic update of Adobe Lightroom and Mac OSX Sierra. This is VERY annoying. Please provide me with a fix. I need the PRESETS to apply to each photo that comes in from tethered capture. Tethering does bring in the photos without any issue, however, the PRESETS get applied to only some photos or won't apply at all, and it's extremely frustrating and dysfunctional when I am doing STOP-MOTION photography and I need to compare shots with the same presets. Please advice and help me resolve this.
Please check Lightroom to see the specific version you are using. The latest update is Lightroom CC 2015.8 / LR 6.8.
I have the most up to date software, and the problem continues. Below are my specs:
Lightroom version: CC 2015.8 [ 1099473 ]
License: Creative Cloud 22.214.171.1245
Operating system: Mac OS 10
Version: 10.12 
Application architecture: x64
Logical processor count: 8
Processor speed: 2.5 GHz
Built-in memory: 16,384.0 MB
Real memory available to Lightroom: 16,384.0 MB
Real memory used by Lightroom: 947.4 MB (5.7%)
Virtual memory used by Lightroom: 1,780.2 MB
Memory cache size: 361.0 MB
Maximum thread count used by Camera Raw: 8
Camera Raw SIMD optimization: SSE2,AVX,AVX2
Displays: 1) 2880x1800, 2) 1920x1080
Graphics Processor Info:
AMD Radeon R9 M370X OpenGL Engine
Check OpenGL support: Passed
Vendor: ATI Technologies Inc.
Version: 4.1 ATI-1.48.16
Renderer: AMD Radeon R9 M370X OpenGL Engine
Application folder: /Applications/Adobe Lightroom
Library Path: /Users/FelixEduardo/Pictures/Lightroom/Lightroom Catalog.lrcat
Settings Folder: /Users/FelixEduardo/Library/Application Support/Adobe/Lightroom
2) Aperture/iPhoto Importer Plug-in
3) Canon Tether Plugin
6) Keyboard Tamer
7) Leica Tether Plugin
8) Nikon Tether Plugin