May i know are you trying to do the panorama in Lightroom itself or using edit in feature to use panorama in Photoshop.
It's probably best to create panorama before you do other work to the images. Then do all of your spot removal and other adjustments on the panorama image itself.
I am merging to panorama in Lightroom.
I would rather not spot the resulting panorama DNG file that Lightroom's panorama merge produces for two reasons:
- It is extremely slow - others have mentioned that Lightroom's spotting abilities are glacially slow when working on large files and I have found this to be the case
- It is more efficient to spot one file and copy the spots over to the others because the spots always appear in the same place
I'm just telling you what the Adobe people have said in the past. They have indicated that it's best to do the panorama first before you do any adjustments. I think the thing that's different about doing panoramas in Lightroom is that the adjustments are not part of the image, but rather catalog entries. Perhaps you could consider doing your spot adjustments and creating TIF images. Then you can use those TIF files to generate your panorama. Otherwise, your desire should probably be taken up with the Adobe engineers.