Which program and which version?
If Cloud, you may need to do the below
Sign out of your account... Uninstall... run the Cleaner...
-http://helpx.adobe.com/creative-cloud/help/install-apps.html (and uninstall)
-using the cleaner after uninstalling and before reinstalling is often needed
-Restart your computer... Sign in to your account... Reinstall the latest version
If an older serial number version of your unnamed program, read below
An idea that MAY work to install and/or run old programs in Windows 10