Nobody can tell you anything without exact system info or other technical details like what specifics of the project you are trying to load. Vague descriptions are of no use to anyone.
Mylenium is right, we don't have nearly enough information to help you.
For example, does it do it on every project or just one?
Also, all of this information too: FAQ: What information should I provide?
I try to load a project from VideoBlock an I receive a message "not responding" I have windows 10 Familly Edition version 1511. I have 16 GO virtual memory and a 64 bits processor. Do you have enough infos or I have to write more. Are you able to help me or not? It's also the same thing when I create my own project.
What processor and what speed?
How much RAM?
What version of AE?