When you're having problems select the layer that is giving you trouble and press the "u" key twice to reveal all modified properties. I'm guessing that scale is not at 100%. If you are having trouble with an asset, like that Photoshop layer, it is also a good idea to select the asset in the project panel so we can see its properties. There's no way we can tell anything from your screenshot because we don't know what you've done to the layers.
At the bottom of the composition window, try changing the resolution from "quarter" to "full".