Nobody can tell you anything without proper system info or other technical details.
Thank you Bob,
I just wasn't sure what details were relevant.
All my Adobe software is up to date.
Windows 7 Pro 64
Dual Xeon 2.6GHz 48 core
128 GB ram
Quadro M6000 Driver version 354.56
3 x HP DreamColor 27"
Yes AE has run successfully on my system I am on Service Pack 1.
This bug has been a recent development. I don't know if it was an Adobe update that started the issues.
My OS and programs are on a OCZ REVOdrive 960GB
Try removing all third-party plugins and then launch AE.