It sounds like you have a right-to-left language enabled version installed and you've got the default direction set to right to left for binding and text direction.
OK. But why should it vary from one document to another? I have produced 30 magazines. Up to issue 20 all was well, after that, this problem exists in all documents, so I did something to swap this binding and text direction, which I cannot discover the reason for - or the remedy to. If I open and brand new document, the problem is there.
A change to your defaults would no affect existing files.
I don't run a RTL version, so I can't tell (or show) you where those settings are. Sorry.