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My experience with upgrading to Windows 10 was a good one. I did an upgrade installation, not a clean install. After the upgrade completed Lightroom, Photoshop, and all my other applications worked normally. No problems whatsoever. I have since installed a SSD drive, replacing my old C drive that contains all of my programs. I still find everything working as expected without any problems.
As of now there are no major issues reported when working Lightroom CC 2015 with Windows 10.
So you may upgrade to the latest version of Windows.
I upgraded from Windows 7 to Windows 10 on two PCs--desktop and Dell laptop. Both were upgrades, not clean installs, and both have SSDs as the C: drive. LR and PS CC 2015 continued to work perfectly after the upgrade on both PCs. Same for Adobe Muse.
If you happen to use Datacolor's Spyder hardware and software to profile and calibrate your monitor, you may find that you get an error when you first do a calibration after upgrading to Windows 10. The error says the profile can't be saved. The solution is simple: use a new name for the profile.
Good luck with the upgrade!