CS5 is not officially supported on Windows 10 (and is not necessarily compatible, though you may get it to work), so rolling back to Win 7 is well worth considering. We see more reports of problems with Win7-Win10 upgrades than those from Win 8, and the general advice is to clean install everything, but that won't change the compatibility issues. Running ID in Windows 7 compatibility mode may help.
Are you saying that no keyboard shortcuts work, or just a custom set? Have you checked Edit > Keyboard Shortcuts... to see what set is in use?
Thank you for your reply.
No shortcuts are working and none are selected to be in use. There are no options when I press the arrow next to Set and nothing happens when selecting New Set. I am actually using a French version of ID (I live in France) and thought maybe it has something to do with keyboard settings, but nothing happens when I change keyboard from US to French
I think you'll need to try a reinstall.
I think you are right Peter as I can't seem to get it working properly. I will probably go back to Windows 7 as I know this works.