When opening DW the loader gets stuck on "initializing Extension Data". Most the time it will sit here forever, very few starts it will open DW but it will be a empty window with just the mini - max - close icons.
Has DW ever worked on your W10 machine?
If not, try this: Solution for installing or opening Dreamweaver issues on Windows 10
If it has worked in the past in the same OS, were you running the Cleaner Tool during your unnistall/reinstalls?