Your question is impossibly vague. Be more specific.
Yeah there are tons of different ways you could animate a speech bubble so it's not really clear what you're looking for. But you might find this tutorial helpful: How to Animate A Speech Bubble in Adobe Flash CC - Mr. H - YouTube
Ok thanks for link, thats one way to do it. Ive got another one in mind that does not look hand drawn. But I am not up to making it yet I have to do other things first. If I run into trouble i'll detail it and ask for specifics.