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Welcome to the wonderful world of non-Adobe PDF viewers...
The Chrome browser does not use Adobe's PDF viewer plug-in (installed via either Adobe Acrobat or the free Adobe Reader) anymore. The Chrome developers starting to block access of plug-ins of a certain type (the type that among others the Adobe PDF viewer uses) a few years ago. This means that you are stuck with the built-in viewer that Chrome comes with. This is a Chrome issue, even though some PDF files do not trigger this problem. Because it is Chrome's PDF viewer, anything that goes wrong is a Chrome problem.
The only thing you can do (besides reporting this to the Chrome developers) is to instruct your users to not open the PDF file in Chrome, but download it instead, and then open it using Acrobat or the free Adobe Reader.
Thanks for your response. This is really useful in terms of understanding the problem.
Sadly (and this is in no way aimed at you) it doesn't help resolve my problem.
I've reported the issue to Chrome who seem less then bothered about solving it.
Thanks for your help.