Buy two separate layouts, do you mean two separate .muse files or just separate phone/tablet layout within a same?
Please explain me a little more what exactly you are trying to achieve, so that I can suggest you the best thing?
I've built sites in Dreamweaver, Wordpress and drag and drop platforms such as Wix and Weebly. All those platforms scale down to mobile (for the most part) without major issues. I tried using Muse a few years ago and I was hoping the current version would work better in this regard. In other words, Muse doesn't support mobile as yet so until it does, is there a widget to merge my Alternate (mobile) page layout with my Desktop layout?
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I figured out what the issue is. I misunderstood the program. Muse is a development tool and not an authoring platform. You still need code to complete. I thought Muse could build responsive websites without coding, or at least that how it is promoted. The marketing is very confusing. However, as a dev tool it makes sense to me once I import the HTML and CSS into Dreamweaver. So Muse more or less replaces Photoshop as a layout tool but you still need to import into Dreamweaver to complete.
Please pardon the confusion.