In Internet Explorer it will simply not download and in Opera it is enabled but it will only work on some things. It will not work for games (crashes browser) and will only play video from some sites.
We are aware of the issue with Flash Player 23 on Vista and Opera. This issue is covered extensively at Adobe Trouble-About to give up [How to reinstall Flash Player for Opera and IE on Vista?] . You may want to follow that topic (click on the 'Follow' link in the upper right".
For the issue with IE, what version of IE are you using? What happens when you try to download the installer? Or does it download, but not launch?
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This issue is fixed in the latest release 18.104.22.168, released today.