I set up the panels (I remove map, slideshow, printing, etc)… I set the background color… I open the panels I usually work with. And EVERY TIME I reopen this new version it acts like I'm starting new…. I get the damn tips (I keep turning them off but it does no good) and everything else reverts back to the way it was… the tips come up again.
I've got work to do, and I'm really annoyed now. I need to not upgrade my LR!
What is your OS and exact version of LR?
Sounds like the user account you are working with does not have full access rights to all folders needed by LR.
What if you run LR as Administrator?