Using updated Windows 10 64 bit OS. Reinstalled Adobe Reader. Copied files in pdf format to a flash drive but when trying to open after plugging in flash drive the first file will open and then get error message and access denied when trying to open subsequent pdf files in the same folder. Alternatively get message You don't have permission to open this file contact the file owner or administrator to obtain permission. Same messages occurs when using Acrobat X.
Can open these same file using Reader on a machine using WIndows 7 with no problems. Can also open files and save them if sent as attachments to an email from the other computer.
Have checked for updates and none listed for either Reader or Acrobat X. I can work aroud this but need to copy numerous from library resources and this is very cumbersome.
Sounds like you have a permissions issue with that disk. See if this fixes the issue:
I hope these instructions work for Windows 10. You may need to move all the PDFs into a folder for this to work.