I am having the same problem. All my apps in CS4 Desing Premium install and work just fine. Only Flash CS4 is giving me headaches. Hours on the phone with Adombe tech support have failed to resolve the issue. Last left at "reinstall Vista 64 and reinstall CS4 Design Premium." Doing so requires 2 to 2.5 days for the installations and upgrades, and, there's no guarantee it will work.
Does anyone have a solution? Adobe? Class?
cs4 has significant problems if you have a corrupt font.
use fontdoctor or some other software to check your fonts.