On this portrait ground work was done in Lightroom and fine details work in Photoshop where I removed some imperfections, soften wrinkles, etc. (using blank layers)
Now they decided to go with a completely different look for the photo and we've generated a new LR output. Back in Photoshop now all the spot healing brush doesn't work of course because the source image has changed.
I was wondering if there would be a way to tell photoshop to re-generate the healing brush work by sampling the new updated layer? It's the exact same photo only colors, contrast and shadows/highlights have changed.
I assume this is a common issue with people but couldn't confirm if I had to start from scratch or not.
No and no. Your workflow is simply unsuitable. You would generate a "neutral" image in LR and do any grading and stylization in PS and of course when doing so would employ proper technique by using duplicate layers with masks, frequency separation and all the good stuff that allows to work "non-destructively" within a certain range and transfer results to updated underneath layers. As it is, you simply have to start over.
You're right, my workflow was unsuitable, thank you. I am discovering frequency separation and wow !... I had been editing in prehistoric times!
Hopefully people doing the same mistakes I was and looking for a way to fix them will stumble here...