When I open InDesign on my Mac (with plenty of space and speed) it painfully slows down my entire computer. I'm talking a 60 second delay. My mouse moves around just fine, but everything else takes forever to load or do anything - even the preferences tab to force quite took many minutes. I tried updating it, and it still happened. I tried uninstalling and reinstalling CC 2015 to see if I could work on that instead, and the problem only got way worse. I eventually was able to uninstall that. Now I don't know what to do. I don't use it very often, however I use Illustrator CC every day and have absolutely no issues there. Got any tips?
Try some of the suggestions in these articles: