Photoshop is randomly corrupted files which are then no longer capable of opening. I really need to know why the program is corrupting the files not how to fix them.
You'll need to provide a lot more information before anyone can help you.
File types that are being corrupted (.psd, .jpg etc.)?
What sort of hardware (desktop, laptop)? If laptop are you using battery or mains power?
Do you get many system crashes? Were the corrupt files being saved when a crash occurred?
What you were doing when these files become corrupted (saved and returned later)?
Any other relevant information?