did you check your brush presets?
I just did, and it didn't do anything.
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Sorry for the pressure trouble. Have you gone through the Photoshop Cafe tutorial for pressure here? Customize Wacom pen and pressure settings in Photoshop tutorial - YouTube
Can you post a screenshot of what your Brush panel looks like in the Shape Dynamics section?
You might try replacing the nib of the pen. I've had crud accumulare just enough to make it act erratically. May not be the issue, but simple enough to try.