Hi Robert ,
This forum is dedicated for queries related to Adobe target . As per the query it seems to be more related to Adobe Photoshop Hence we are moving the query to respective forum.
Nobody can tell you anything without exact system info or other technical details such as actual details about the document and what filters you intend to use. Spitting bullet points out of context is of no use to anyone.
Please post screenshots.
What are the image’s Color Mode and bit depth?