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It sounds like somehow your copy of InDesign got corrupted. The usual recommended way to "fix" the program is to delete the application preferences. I can't say that doing so will help save an already corrupted file but it may prevent it from happening to you again.
To reset preferences:
For Macintosh Users: With InDesign closed launch a Finder Window in column view and click on your home folder. With the Option Key pressed choose Library from the Finder Go Menu. Within the Library folder find the following two files and delete them: “Adobe InDesign” and “com.adobe.InDesign.plist”. When InDesign is next launched it will create new preference files and the program will be restored to its defaults.
After you’ve reset up the program (make sure that no document window is open) to your liking, it is a really good idea to create copies of your personalized “mint” preference files (make sure that you quit the program before copying them—that finalizes your customization) and use them in the future to replace any corrupt versions you may need to delete.
For Windows Users: Hold down Ctrl + Alt + Shift when launching InDesign and respond affirmatively when asked if you want to reset.
Once InDesign has been cleaned up try opening your corrupt file both in its original form and the IDML version. If you are able to open the file and work on it I would not save anything until you're sure that the program is now allowing you to move forward on the file without further corruption. If it is the same as before I would force quit InDesign so as not to corrupt the new preference files.
Thanks but it's not corrupted. Still having the same issue. It happened again today and I'm working like usual. Now I'm just having to pay attention that all my pages are in my catalog before saving! Very frustrating
This does not work for me. It is marked as the correct answer - it may work for some users but does not universally resolve the issue.
Sounds more like a corrupt file. Export it to IDML and then try working on that file.