Having just got a new iMac 27" 5K Retina with a AMD Pro 580 GPU, I'm finding that if I use GPU preview mode in Indesign CC 2017 12.1.56, my spreads all display with colour profiles badly out of sorts. If I switch on "Proof Colors" they are ok.
Interestingly my page thumbnails, when displayed in the pages flyout panel, show in the right colour, even as the panel overlaps the spreads that are looking wrong.
If I switch to CPU preview mode, everything comes back to being colour profiled again - and I don't need to have "Proof Colors" ticked.
Images look totally fine on same machine with GPU acceleration enabled in Photoshop and Lightroom.
Anybody else having similar problems, with ideas on what is causing this?
In order to help assist you further on your query we need some more information like:
Exact version of MAC OS
If you create new document different pictures , does it shows the same error?
Also when you change secondary graphic card to primary and vice versa , then check how application responds and share results.