This sounds like a broken monitor profile.
Adobe applications use the monitor profile to display images, but most other applications don't, and will be unaffected by a broken profile.
I'm going to guess (although I may be wrong) that you're on Windows 10, which is known to install low quality/defective profiles from monitor manufacturers when doing updates.
As a possible temporary fix, try setting the monitor profile to sRGB (Adobe RGB if you have a wide gamut monitor).
If this fixes the issue, calibrate your monitor with a hardware calibrator as soon as possible.
This will create a profile that accurately describes your monitor.
If you are on Windows, press the Windows key + R, and type colorcpl in the box and press Enter.
Add the sRGB (or Adobe RGB) profile, then set it as Default profile. See screenshot (from Windows 7) below.
If you have a Mac, follow the instructions here:
Are you using ICC color profiles? Maybe the one you're using got corrupted in some way.
THANK YOU SO MUCH - It was a busted monitor profile - and yes Windows 10 system... but problem is SOLVED!!!