You need to provide a lot more info, what version of Photoshop and OS do you have, system specs would also help, what's the size of the file you're trying to save.
The more info you provide the easier it is for us to help you!
Hi, That's happen in all the versions but if you need some version I tell you Photoshop CC. I need the file the most size possible because I have to do a poster. Thanks for your interest.